Estudio de la difusión de la luz mediante C-Quant(R) en pacientes con distrofia endotelial de Fuchs: un estudio piloto / of light scattering using C-Quant(R) in patients with Fuchs' endothelial dystrophy: A pilot study

Objetivo: La finalidad de este trabajo fue determinar la difusión de la luz en pacientes con distrofia endotelial de Fuchs sin edema corneal clínicamente significativo, y evaluar su relación con el recuento de células endoteliales, paquimetría y parámetros biomecánicos corneales. Materiales y métodos: Los valores de difusión de la luz fueron medidos usando el C-Quant(R) (Oculus Optikgeräte GmbH, Alemania) en 32 ojos de 17 pacientes diagnosticados de distrofia endotelial de Fuchs sin edema corneal clínicamente significativo. Las propiedades biomecánicas corneales fueron determinadas usando ORA y Corvis ST(R). Resultados: El 93,8% de los ojos estudiados mostraron un valor de difusión de la luz fuera del rango normal. No se encontró ninguna correlación estadísticamente significativa (p > 0,05) entre los valores de difusión de la luz medidos mediante el C-Quant(R) y el recuento endotelial, la paquimetría o las propiedades biomecánicas corneales. Conclusiones: En nuestro estudio encontramos una alteración en los valores de difusión de la luz de los pacientes con distrofia endotelial de Fuchs. Esta alteración no parece correlacionarse significativamente con la gravedad de la enfermedad (AU)

Objective: The purpose of this study was to determine the light scattering in patients with Fuchs' endothelial dystrophy without clinically significant corneal oedema, and evaluate its relationship with endothelial cell count, corneal thickness, and corneal biomechanical parameters. Materials and methods: The values of light scattering were measured by C-Quant(R) (Oculus Optikgeräte GmbH, Germany) in 32 eyes of 17 patients diagnosed with Fuchs' endothelial dystrophy without clinically significant corneal oedema. Corneal biomechanical properties were determined using ORA (ocular response) and Corvis ST(R) (tonometry). Results: A light scattering value outside the normal range was observed in 93.8% of eyes studied. No statistically significant association (P>.05) was found between the values of the measured light scattering by C-Quant(R) and endothelial count, pachymetry, or corneal biomechanical properties. Conclusions: In this study, changes were found in the values of light scattering values of patients with corneal Fuchs' endothelial dystrophy. This change does not appear to correlate significantly with disease severity (AU)

Study of light scattering using C-Quant® in patients with Fuchs' endothelial dystrophy: A pilot study. / Estudio de la difusión de la luz mediante C-Quant® en pacientes con distrofia endotelial de Fuchs: un estudio piloto.

OBJECTIVE: The purpose of this study was to determine the light scattering in patients with Fuchs' endothelial dystrophy without clinically significant corneal oedema, and evaluate its relationship with endothelial cell count, corneal thickness, and corneal biomechanical parameters. MATERIALS AND METHODS: The values of light scattering were measured by C-Quant® (Oculus Optikgeräte GmbH, Germany) in 32 eyes of 17 patients diagnosed with Fuchs' endothelial dystrophy without clinically significant corneal oedema. Corneal biomechanical properties were determined using ORA (ocular response) and Corvis ST® (tonometry). RESULTS: A light scattering value outside the normal range was observed in 93.8% of eyes studied. No statistically significant association (P>.05) was found between the values of the measured light scattering by C-Quant® and endothelial count, pachymetry, or corneal biomechanical properties. CONCLUSIONS: In this study, changes were found in the values of light scattering values of patients with corneal Fuchs' endothelial dystrophy. This change does not appear to correlate significantly with disease severity.